5l1d

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Structure of rabbit RyR2 in complex with FKBP12.6 in a closed state (conformation C1)Structure of rabbit RyR2 in complex with FKBP12.6 in a closed state (conformation C1)

Structural highlights

5l1d is a 8 chain structure with sequence from Human and Oryctolagus cuniculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
NonStd Res:
Gene:FKBP1B, FKBP12.6, FKBP1L, FKBP9, OTK4 (HUMAN)
Activity:Peptidylprolyl isomerase, with EC number 5.2.1.8
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT
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Function

[FKB1B_HUMAN] Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

See Also

5l1d, resolution 10.50Å

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OCA