6gap

Crystal structure of the T3D reovirus sigma1 coiled coil tail and bodyCrystal structure of the T3D reovirus sigma1 coiled coil tail and body

Structural highlights

6gap is a 3 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[SIGM1_REOVD] Fiber-like molecule that attaches the virion to the host cell membrane by binding to the primary receptor F11R/JAM-A and to sialic acid containing proteins (coreceptor). The interaction of sigma-1 with F11R is required for NF-kB activation and apoptosis. Binding to both sialic acid and F11R is required to induce maximal levels of apoptosis.

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

6gap

Crystal structure of the T3D reovirus sigma1 coiled coil tail and bodyCrystal structure of the T3D reovirus sigma1 coiled coil tail and body

Structural highlights

Function

Contents

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Navigation menu

6gap

Crystal structure of the T3D reovirus sigma1 coiled coil tail and bodyCrystal structure of the T3D reovirus sigma1 coiled coil tail and body

Structural highlights

Function

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Navigation menu

Search