5x8c

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AMPPCP and TMP bound crystal structure of thymidylate kinase from thermus thermophilus HB8AMPPCP and TMP bound crystal structure of thymidylate kinase from thermus thermophilus HB8

Structural highlights

5x8c is a 2 chain structure with sequence from Thet8. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Gene:tmk, TTHA1607 (THET8)
Activity:dTMP kinase, with EC number 2.7.4.9
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[KTHY_THET8] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.

5x8c, resolution 2.07Å

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OCA