Crystal Structure of IPMDH from Sulfolobus tokodaiiCrystal Structure of IPMDH from Sulfolobus tokodaii

Structural highlights

1wpw is a 2 chain structure with sequence from Dsm 16993. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:3-isopropylmalate dehydrogenase, with EC number 1.1.1.85
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[LEU3_SULTO] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

1wpw, resolution 2.80Å

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OCA