6cey

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Aminoglycoside Phosphotransferase (2)-Ia in complex with GMPPNP, Magnesium, and Lividomycin moietiesAminoglycoside Phosphotransferase (2)-Ia in complex with GMPPNP, Magnesium, and Lividomycin moieties

Structural highlights

6cey is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[AACA_STAAU] Resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region, and the gentamicin resistance is due to the APH activity encoded by the C-terminal region of the protein.

6cey, resolution 2.40Å

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OCA