6cey
Aminoglycoside Phosphotransferase (2)-Ia in complex with GMPPNP, Magnesium, and Lividomycin moietiesAminoglycoside Phosphotransferase (2)-Ia in complex with GMPPNP, Magnesium, and Lividomycin moieties
Structural highlights
Function[AACA_STAAU] Resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region, and the gentamicin resistance is due to the APH activity encoded by the C-terminal region of the protein. |
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