Alice Clark/ATPsynthase

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ATP SynthaseATP Synthase


The ATP synthase molecule is built up of different proteins

The of the structure

The F1 motor contains and chains.

The F1 also has the Adenosine DiPhosphate (ADP) molecules and the Adenosine TriPhosphate ATP binding sites. See if you can identify the base, sugar and phosphates in these molecules.

axle

stator

The F0 is formed of membrane bound helices


To the right is a structure of ATP synthase shown using the Jmol viewer within Proteopedia.


Exploring in 3D

- left mouse button to rotate the protein model.

- middle mouse button or scroll wheel to zoom (option-click on a Mac)

- right mouse button for more options and information (control-click on a Mac).

Have a go yourself now ==>


Click '>here</scene> for a view where the different components are coloured differently? See how many you can identify



Q1: Where is the F1 region, and what is its role?


Q2: How many ATP can you find?


Q3: What is the location and role of the FO region?



ATP synthase is an example of a molecular motor.

Use the Structure to answer the questions below.


Q4: How many phosphates does ATP have?


Q5: How many phosphates does ADP have




Bovine (Cow) ATP Synthase (PDB entry 5lqz)

Drag the structure with the mouse to rotate


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Alice Clark