5qcc

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Crystal structure of human Cathepsin-S with bound ligandCrystal structure of human Cathepsin-S with bound ligand

Structural highlights

5qcc is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:CTSS (HUMAN)
Activity:Cathepsin S, with EC number 3.4.22.27
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[CATS_HUMAN] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.

5qcc, resolution 1.80Å

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OCA