5nsd

Co-crystal structure of NAMPT dimer with KPT-9274Co-crystal structure of NAMPT dimer with KPT-9274

Structural highlights

5nsd is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:	, ,
Activity:	Nicotinamide phosphoribosyltransferase, with EC number 2.4.2.12
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[NAMPT_HUMAN] Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway (By similarity).

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5nsd

Co-crystal structure of NAMPT dimer with KPT-9274Co-crystal structure of NAMPT dimer with KPT-9274

Structural highlights

Function

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5nsd

Co-crystal structure of NAMPT dimer with KPT-9274Co-crystal structure of NAMPT dimer with KPT-9274

Structural highlights

Function

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