Structure of the Schizosaccharomyces pombe YchF GTPaseStructure of the Schizosaccharomyces pombe YchF GTPase

Structural highlights

1ni3 is a 1 chain structure with sequence from Cbs 356. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
NonStd Res:
Gene:SPAC27E2.03C (CBS 356)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

[OLA1_SCHPO] Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP (By similarity). Negatively regulates the G2/M transition in the cell cycle.[HAMAP-Rule:MF_03167][1]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. Navarro FJ, Nurse P. A systematic screen reveals new elements acting at the G2/M cell cycle control. Genome Biol. 2012 May 24;13(5):R36. doi: 10.1186/gb-2012-13-5-r36. PMID:22624651 doi:http://dx.doi.org/10.1186/gb-2012-13-5-r36

1ni3, resolution 2.80Å

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