6eoo

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DPP8 - Apo, space group 20DPP8 - Apo, space group 20

Structural highlights

6eoo is a 3 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Activity:Dipeptidyl-peptidase IV, with EC number 3.4.14.5
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[DPP8_HUMAN] Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. May play a role in T-cell activation and immune function.[1]

References

  1. Abbott CA, Yu DM, Woollatt E, Sutherland GR, McCaughan GW, Gorrell MD. Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8. Eur J Biochem. 2000 Oct;267(20):6140-50. PMID:11012666

6eoo, resolution 2.50Å

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