Proteopedia

5uii

Revision as of 08:50, 31 January 2018 by OCA (talk | contribs)

structure of DHFR with bound buformin and NADPstructure of DHFR with bound buformin and NADP

Structural highlights

5uii is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Activity:Dihydrofolate reductase, with EC number 1.5.1.3
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.

5uii, resolution 1.35Å

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