5ogs

Crystal structure of human AND-1 SepB domainCrystal structure of human AND-1 SepB domain

Structural highlights

5ogs is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[WDHD1_HUMAN] Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication.^[1]

References

↑ Im JS, Ki SH, Farina A, Jung DS, Hurwitz J, Lee JK. Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15628-32. Epub 2009 Sep 8. PMID:19805216 doi:http://dx.doi.org/0908039106

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OCA

[1] Im JS, Ki SH, Farina A, Jung DS, Hurwitz J, Lee JK. Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And-1, RecQL4, and Mcm10 proteins. Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15628-32. Epub 2009 Sep 8. PMID:19805216 doi:http://dx.doi.org/0908039106

[1]

5ogs

Crystal structure of human AND-1 SepB domainCrystal structure of human AND-1 SepB domain

Structural highlights

Function

References

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5ogs

Crystal structure of human AND-1 SepB domainCrystal structure of human AND-1 SepB domain

Structural highlights

Function

References

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