5m7c

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Blood group synthase AAGlyB in complex with UDP and cryoprotected with PEG 3350Blood group synthase AAGlyB in complex with UDP and cryoprotected with PEG 3350

Structural highlights

5m7c is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[BGAT_HUMAN] This protein is the basis of the ABO blood group system. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity.

5m7c, resolution 1.60Å

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OCA