Structural highlights
3wzw is a 1 chain structure with sequence from Sheon. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , |
| Related: | 3wzv, 3wzx, 3wzy |
| Gene: | leuB, SO_4235 (SHEON) |
| Activity: | 3-isopropylmalate dehydrogenase, with EC number 1.1.1.85 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[LEU3_SHEON] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.