Structural highlights
3vpm is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , |
| Related: | 3olj, 3vpn, 3vpo |
| Gene: | RR2, RRM2 (HUMAN) |
| Activity: | Ribonucleoside-diphosphate reductase, with EC number 1.17.4.1 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[RIR2_HUMAN] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.