Crystal structure of Tm1821, the 8-oxoguanine DNA glycosylase of Thermotoga maritimaCrystal structure of Tm1821, the 8-oxoguanine DNA glycosylase of Thermotoga maritima

Structural highlights

3n0u is a 3 chain structure with sequence from Atcc 43589. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:ogg, Tm1821, TM_1821 (ATCC 43589)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[OGG1_THEMA] Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites) (By similarity).

3n0u, resolution 1.50Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA