3fb2
Crystal structure of the human brain alpha spectrin repeats 15 and 16. Northeast Structural Genomics Consortium target HR5563a.Crystal structure of the human brain alpha spectrin repeats 15 and 16. Northeast Structural Genomics Consortium target HR5563a.
Structural highlights
Disease[SPTN1_HUMAN] West syndrome. The disease is caused by mutations affecting the gene represented in this entry. Function[SPTN1_HUMAN] Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. |
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Human
- Acton, T B
- Ciccosanti, C
- Foote, E L
- Hunt, J F
- Janjua, H
- Montelione, G T
- Structural genomic
- Seetharaman, J
- Shastry, R
- Su, M
- Tong, L
- Vorobiev, S M
- Xiao, R
- Actin capping
- Actin-binding
- Alternative splicing
- Brain spectrin
- Calcium
- Calmodulin-binding
- Cytoplasm
- Cytoskeleton
- Fordrin alpha chain
- Hr5563a
- Nesg
- Non-erythroid alpha chain alpha-ii spectrin
- Phosphoprotein
- Polymorphism
- PSI, Protein structure initiative
- Sh3 domain
- Spectrin alpha chain
- Spta2 human
- Sptan1
- Structural protein