Crystal structure of TrmH family RNA methyltransferase from Burkholderia pseudomalleiCrystal structure of TrmH family RNA methyltransferase from Burkholderia pseudomallei

Structural highlights

3e5y is a 2 chain structure with sequence from Burkholderia pseudomallei 305. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:BURPS305_4843 (Burkholderia pseudomallei 305)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[A4LJP7_BURPE] Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.[HAMAP-Rule:MF_01885]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

3e5y, resolution 2.40Å

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OCA