Proteopedia

3b7k

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Human Acyl-coenzyme A thioesterase 12Human Acyl-coenzyme A thioesterase 12

Structural highlights

3b7k is a 3 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:ACOT12, CACH, CACH1, STARD12 (HUMAN)
Activity:Acetyl-CoA hydrolase, with EC number 3.1.2.1
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[ACO12_HUMAN] Hydrolyzes acetyl-CoA to acetate and CoA.[1]

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Suematsu N, Isohashi F. Molecular cloning and functional expression of human cytosolic acetyl-CoA hydrolase. Acta Biochim Pol. 2006;53(3):553-61. Epub 2006 Sep 2. PMID:16951743

3b7k, resolution 2.70Å

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