5tpk
Crystal Structure of Mouse Protocadherin-15 EC7-8 V875ACrystal Structure of Mouse Protocadherin-15 EC7-8 V875A
Structural highlights
Disease[PCD15_MOUSE] Defects in Pcdh15 are the cause of the Ames waltzer (av) phenotype. It is characterized by deafness and a balance disorder, associated with the degeneration of inner ear neuroepithelia. Function[PCD15_MOUSE] Calcium-dependent cell-adhesion protein. Required for inner ear neuroepithelial cell elaboration and cochlear function. Probably involved in the maintenance of normal retinal function. |
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