Leukocyte immunoglobulin-like receptor

Leukocyte immunoglobulin-like receptors (LIR) or CD85 have extracellular immunoglobulin domains. LIR modulates a variety of immune cells. LIR interacts with class I MHC molecules.

spinqualitylabelsall models Structure of human leukocyte immunoglobulin-like receptor ligand-binding domain (salmon) complex with class I MHC (aqua), β-2 microglobulin (green) and POL polyprotein peptide (pink) (PDB entry 1p7q) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D structures of leukocyte immunoglobulin-like receptor3D structures of leukocyte immunoglobulin-like receptor

Updated on 09-August-2017

{"openlevels":0}

• LIR-1
  • 1g0x, 1ufu – hLIR-1 ligand-binding domain D1D2– human
    
  • 1ugn, 1vdg – hLIR-1 ligand-binding domain D1D2 (mutant)
    
  • 4ll9 – hLIR-1 ligand-binding domain D3D4
    
• LIR-2
  • 4lla – hLIR-2 ligand-binding domain D3D4
    
  • 2otp – hLIR-2 ligand-binding domain D1D2
    
  • 2dyp – hLIR-2 ligand-binding domain D1D2 + class I MHC + β-2 microglobulin + H2A peptide
    
• LIR-4
  • 3q2c – hLIR-4 N-terminal domain
    
• LIR-5
  • 3p2t – hLIR-5 ligand-binding domain D1D2
    
• LIR-1 complexes
  • 1p7q – hLIR-1 ligand-binding domain D1D2 + class I MHC + β-2 microglobulin + POL polyprotein peptide
    
  • 5knm – hLIR-1 ligand-binding domain D1D2 + class I MHC + β-2 microglobulin + peptide
    
  • 4no0 – hLIR-1 ligand-binding domain D1D2 + class I MHC + β-2 microglobulin + lymphocyte-specific protein peptide
    
  • 3d2u – hLIR-1 ligand-binding domain D1D2 + herpesvirus UL18 + β-2 microglobulin + actin peptide