Contactin

Function Contactin (CNTN) is a neuronal cell surface glycoprotein which associates with sodium channel and enhances the density of these channels on the plasma membrane in mammalian expression systems. Disease contactin-4 is an autism susceptibility locus.

spinqualitylabelsall models Mouse contactin-3 domains Ig1-Ig4 complex with glycerol (PDB code 5i99) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D structures of contactin3D structures of contactin

Updated on 29-January-2017

{"openlevels":0}

• Contactin-1
  • 5e53 – CNTN FN1-FN3 domains – chicken
    
  • 3s97 – hCNTN Ig2-Ig3 domains + receptor-type tyrosine-protein phosphatase zeta - human
    
  • 2ee2 – hCNTN FN3 domains - NMR
    
• Contactin-2
  • 5e7l – mCNTN FN1-FN3 domains – mouse
    
  • 2om5 – hCNTN Ig1-Ig4 domains
    
• Contactin-3
  • 5e4q – mCNTN FN1-FN3 domains
    
  • 5i99 – mCNTN Ig5-FN2 domains
    
  • 5e5r – mCNTN Ig2-Ig3 domains + receptor-type tyrosine-protein phosphatase gamma
    
• Contactin-4
  • 5e4s – mCNTN FN1-FN3 domains
    
  • 3jxa – mCNTN Ig1-Ig4 domains
    
  • 3kld – mCNTN Ig2-Ig3 domains + receptor-type tyrosine-protein phosphatase gamma
    
• Contactin-5
  • 5e4i – mCNTN Ig1-Ig4 domains
    
  • 5e52 – hCNTN FN1-FN3 domains
    
  • 4n68 – hCNTN FN3 domains
    
• Contactin-6
  • 5e55 – mCNTN FN1-FN3 domains
    
  • 5e5u – mCNTN Ig2-Ig3 domains + receptor-type tyrosine-protein phosphatase gamma