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5hh4

Revision as of 03:40, 19 January 2017 by OCA (talk | contribs)

Crystal structure of metallo-beta-lactamase IMP-1 in complex with a phosphonate-based inhibitorCrystal structure of metallo-beta-lactamase IMP-1 in complex with a phosphonate-based inhibitor

Structural highlights

5hh4 is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , ,
Activity:Beta-lactamase, with EC number 3.5.2.6
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[BLAB_SERMA] Confers resistance to imipenem and broad-spectrum beta-lactams. Also hydrolyzes carbapenems.

5hh4, resolution 2.00Å

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OCA
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