User:Kerry Frattarola/Sandbox 1

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Human Immunodeficiency Virus protease inhibitorHuman Immunodeficiency Virus protease inhibitor

Indinavir, better known as Crixivan, (1hsg)

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<StructureSection load='1stp' size='340' side='right' caption='Caption for this structure' scene=>

Structure

Function

Mechanism

Indinavir acts with the Asp25, Thr26 and Gly27 subunits in the HIV-1 protease enzyme.[1]

Cellular Effects

Structure of HIV-1 protease mutant bound to indinavir, (2b7z), resolution 2.20Å

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ReferencesReferences

  1. Mager PP. The active site of HIV-1 protease. Med Res Rev. 2001 Jul;21(4):348-53. PMID:11410934