Human Aldose Reductase in Complex with NADP+ and WY14643 in Space Group P212121Human Aldose Reductase in Complex with NADP+ and WY14643 in Space Group P212121

Structural highlights

5ha7 is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Activity:Aldehyde reductase, with EC number 1.1.1.21
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.

5ha7, resolution 1.65Å

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OCA