Structural highlights
5d08 is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , , |
| NonStd Res: | |
| Related: | 5d0a, 5d0b |
| Activity: | Epoxyqueuosine reductase, with EC number 1.17.99.6 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[QUEG_BACSU] Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).[HAMAP-Rule:MF_00916][1]
References
- ↑ Miles ZD, McCarty RM, Molnar G, Bandarian V. Discovery of epoxyqueuosine (oQ) reductase reveals parallels between halorespiration and tRNA modification. Proc Natl Acad Sci U S A. 2011 May 3;108(18):7368-72. doi:, 10.1073/pnas.1018636108. Epub 2011 Apr 18. PMID:21502530 doi:http://dx.doi.org/10.1073/pnas.1018636108