5k95

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Crystal Structure of GTP Cyclohydrolase-IB with 8-oxo-GTPCrystal Structure of GTP Cyclohydrolase-IB with 8-oxo-GTP

Structural highlights

5k95 is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
NonStd Res:
Activity:GTP cyclohydrolase I, with EC number 3.5.4.16
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[GCH4_NEIG1] Converts GTP to 7,8-dihydroneopterin triphosphate.[1]

References

  1. El Yacoubi B, Bonnett S, Anderson JN, Swairjo MA, Iwata-Reuyl D, de Crecy-Lagard V. Discovery of a new prokaryotic type I GTP cyclohydrolase family. J Biol Chem. 2006 Dec 8;281(49):37586-93. Epub 2006 Oct 10. PMID:17032654 doi:10.1074/jbc.M607114200

5k95, resolution 2.77Å

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