RmlC

Function RmlC is an enzyme of the dTPD-rhamnose pathway. Deoxy-thymidine diphosphate (dTDP)-L-rhamnose is the precursor of L-rhamnose. L-rhamnose is a sugar component of microbial cell wall and is absent in human. Relevance Inhibitors of RmlC can serve as potential antimicrobial drugs.

spinqualitylabelsall models Structure of RmlC complex with dTPD-rhamnose (PDB code 2ixc). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D structures of RmlC3D structures of RmlC

Updated on 17-August-2016

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• RmlC
  • 1pm7, 1upi – MtRmlC – Mycobacterium tuberculosis
    
  • 2ixj, 1rtv – PaRmlC – Pseudomonas aeruginosa
    
  • 1nxm – SsRmlC – Streptococcus suis
    
  • 1ep0 – MetRmlC – Methanothermobacter thermautotrophicus
    
  • 1dzr – StRmlC – Salmonella typhimurium
    
• RmlC complexes
  • 2ixc – MtRmlC + dTDP rhamnose
    
  • 2ixh – PaRmlC + dTDP rhamnose
    
  • 2ixl – SsRmlC + dTDP rhamnose
    
  • 2ixk – PaRmlC + dTDP-keto rhamnose
    
  • 1nyw – SsRmlC + dTDP glucose
    
  • 1nzc – SsRmlC + dTDP xylose
    
  • 1epz – MetRmlC + TDP
    
  • 3ryk – RmlC + TDP + pyrophosphate – Bacillus anthracis
    
  • 1dzt – StRmlC + acetylthymidine diphosphate