4iy4

From Proteopedia
Revision as of 12:51, 11 August 2016 by OCA (talk | contribs)
Jump to navigation Jump to search

Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4

Structural highlights

4iy4 is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Gene:CNNM2 (HUMAN)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

[CNNM2_HUMAN] Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry.

Function

[CNNM2_HUMAN] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity).

4iy4, resolution 2.90Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA