4l59

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Crystal structure of the 3-MBT repeat domain of L3MBTL3 and UNC2533 complexCrystal structure of the 3-MBT repeat domain of L3MBTL3 and UNC2533 complex

Structural highlights

4l59 is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:L3MBTL3, KIAA1798, MBT1 (HUMAN)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[LMBL3_HUMAN] Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Required for normal maturation of myeloid progenitor cells (By similarity).

4l59, resolution 2.29Å

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OCA