Crystal structure of p19 in complex with double-helical RNA 19mer p(CAG)3C(CCG)3Crystal structure of p19 in complex with double-helical RNA 19mer p(CAG)3C(CCG)3

Structural highlights

4j5v is a 2 chain structure with sequence from Tbsv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:ORF4 (TBSV)
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[P19_TBSVK] Viral suppressor of RNA silencing which binds specifically to silencing RNAs (siRNAs). Acts as a molecular caliper to specifically select siRNAs based on the length of the duplex region of the RNA (By similarity).

See Also

4j5v, resolution 2.15Å

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OCA