3s8c

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Structure of Yeast Ribonucleotide Reductase 1 R293A with AMPPNP and CDPStructure of Yeast Ribonucleotide Reductase 1 R293A with AMPPNP and CDP

Structural highlights

3s8c is a 1 chain structure with sequence from Baker's yeast. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
Gene:CRT7, RIR1, RNR1, Saccharomyces, SDS12, YER070W (Baker's yeast)
Activity:Ribonucleoside-diphosphate reductase, with EC number 1.17.4.1
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[RIR1_YEAST] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.[1]

See Also

References

  1. Domkin V, Thelander L, Chabes A. Yeast DNA damage-inducible Rnr3 has a very low catalytic activity strongly stimulated after the formation of a cross-talking Rnr1/Rnr3 complex. J Biol Chem. 2002 May 24;277(21):18574-8. Epub 2002 Mar 13. PMID:11893751 doi:http://dx.doi.org/10.1074/jbc.M201553200

3s8c, resolution 2.77Å

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