3mpd

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Crystal structure of nucleoside diphosphate kinase from encephalitozoon cuniculi, cubic form, apoCrystal structure of nucleoside diphosphate kinase from encephalitozoon cuniculi, cubic form, apo

Structural highlights

3mpd is a 2 chain structure with sequence from Enccn. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:ECU06_1530, HM-1:IMSS, NDK1 (ENCCN)
Activity:Nucleoside-diphosphate kinase, with EC number 2.7.4.6
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[NDK_ENCCU] Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3mpd, resolution 2.08Å

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