4jos

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Crystal structure of a putative 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Francisella philomiragia ATCC 25017 (Target NYSGRC-029335)Crystal structure of a putative 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Francisella philomiragia ATCC 25017 (Target NYSGRC-029335)

Structural highlights

4jos is a 2 chain structure with sequence from Frap2. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, ,
NonStd Res:
Gene:Fphi_0356 (FRAP2)
Activity:Adenosylhomocysteine nucleosidase, with EC number 3.2.2.9
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[B0TZL4_FRAP2] Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively.[SAAS:SAAS00035153]

4jos, resolution 1.45Å

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