Closed form of murine Acid Sphingomyelinase in complex with bisphosphonate inhibitor AbPAClosed form of murine Acid Sphingomyelinase in complex with bisphosphonate inhibitor AbPA

Structural highlights

5fi9 is a 2 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:, , , , ,
Activity:Sphingomyelin phosphodiesterase, with EC number 3.1.4.12
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

[ASM_MOUSE] Converts sphingomyelin to ceramide. Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol.[UniProtKB:P17405]

5fi9, resolution 2.54Å

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OCA