User:Eric Martz/5eon

The biological unit of 5eon is a crystallographic structure of 6 alpha helices assembled into a fiber with a hydrophobic core. The individual peptides are synthetic and were designed to assemble in this manner, with a hydrophotic core rich in phenylalanine. The crystal structure has a resolution of 1.7 Å (very good), and an Rfree of 0.22, which is average for this resolution, indicating that the model is reliable. The . The Phe rings (dark gray) are surrounded by (light gray). The charges form on the surface, reminiscent of Xiao's theoretical model of the Geobacter sulfurreducens pilus. Sequence The peptide sequence is constructed from 4 copies of heptad E L/F K A I A Q/K/W The amino-terminal Glu is acetylated, removing its positive charge. The C-terminal Lys is amidated, removing its negative charge. Here is the sequence of one complete peptide (29 amino acids) showing the heptad repeats. ELKAIAQ EFKAIAK EFKAIAW EFKAIAQ K

spinqualitylabelsall models Biological unit of 5eon. Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image