5do7

Crystal Structure of the Human Sterol Transporter ABCG5/ABCG8Crystal Structure of the Human Sterol Transporter ABCG5/ABCG8

Structural highlights 5do7 is a 4 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum Disease [ABCG5_HUMAN] Sitosterolemia. The disease is caused by mutations affecting the gene represented in this entry. [ABCG8_HUMAN] Sitosterolemia. Disease susceptibility may be associated with variations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. Function [ABCG5_HUMAN] Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile. [ABCG8_HUMAN] Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.

spinqualitylabelsall models 5do7, resolution 3.93Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image