Metabotropic glutamate receptor

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Structure of the binding domain of the Metabotropic Glutamate Receptor, GluR1, bound to glutamate and gadolinium ions (1isr)

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Metabotropic glutamate receptors are glutamate receptors that activate ion channels indirectly through a signaling cascade involving G proteins[1]. They are members of the large class of seven-transmembrane domain receptors, the G protein-coupled receptors. See also Ligand Binding N-Terminal of Metabotropic Glutamate Receptors.

Articles in Proteopedia concerning Toll-like Receptors include:


3D structures of metabotropic glutamate receptor3D structures of metabotropic glutamate receptor

Updated on 21-April-2016

See AlsoSee Also

Membrane Channels & Pumps
Ionotropic_Glutamate_Receptors
Alzheimer's Disease

ReferencesReferences

  1. Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ, Dingledine R. Glutamate receptor ion channels: structure, regulation, and function. Pharmacol Rev. 2010 Sep;62(3):405-96. doi: 10.1124/pr.109.002451. PMID:20716669 doi:http://dx.doi.org/10.1124/pr.109.002451

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

Wayne Decatur, Michal Harel, Nikki Hunter, Alexander Berchansky