4zwq

Crystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice Type ICrystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice Type I

Structural highlights

4zwq is a 7 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Related:	4zwr, 4zws, 4zwt
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[UVSY_BPT4] Plays a role in viral DNA synthesis by promoting enzymatic activities of UvsX recombinase, by promoting UvsX-ssDNA filament assembly, and by helping UvsX to displace bound gp32 from ssDNA.^[1] ^[2]

References

↑ Pant K, Shokri L, Karpel RL, Morrical SW, Williams MC. Modulation of T4 gene 32 protein DNA binding activity by the recombination mediator protein UvsY. J Mol Biol. 2008 Jul 25;380(5):799-811. doi: 10.1016/j.jmb.2008.05.039. Epub 2008, May 24. PMID:18565541 doi:http://dx.doi.org/10.1016/j.jmb.2008.05.039
↑ Xu H, Beernink HT, Morrical SW. DNA-binding properties of T4 UvsY recombination mediator protein: polynucleotide wrapping promotes high-affinity binding to single-stranded DNA. Nucleic Acids Res. 2010 Aug;38(14):4821-33. doi: 10.1093/nar/gkq219. Epub 2010, Apr 5. PMID:20371513 doi:http://dx.doi.org/10.1093/nar/gkq219

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OCA

[1] Pant K, Shokri L, Karpel RL, Morrical SW, Williams MC. Modulation of T4 gene 32 protein DNA binding activity by the recombination mediator protein UvsY. J Mol Biol. 2008 Jul 25;380(5):799-811. doi: 10.1016/j.jmb.2008.05.039. Epub 2008, May 24. PMID:18565541 doi:http://dx.doi.org/10.1016/j.jmb.2008.05.039

[2] Xu H, Beernink HT, Morrical SW. DNA-binding properties of T4 UvsY recombination mediator protein: polynucleotide wrapping promotes high-affinity binding to single-stranded DNA. Nucleic Acids Res. 2010 Aug;38(14):4821-33. doi: 10.1093/nar/gkq219. Epub 2010, Apr 5. PMID:20371513 doi:http://dx.doi.org/10.1093/nar/gkq219

[1]

[2]

4zwq

Crystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice Type ICrystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice Type I

Structural highlights

Function

References

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4zwq

Crystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice Type ICrystal Structure of the Bacteriophage T4 recombination mediator protein UvsY, Lattice Type I

Structural highlights

Function

References

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