B-DNA tour

B-form DNAB-form DNA

Most common DNA conformation in vivo
Narrower, more elongated helix than A.
Wide major groove easily accessible to proteins
Narrow minor groove
Favored conformation at high water concentrations (hydration of minor groove seems to favor B-form)
Base pairs nearly perpendicular to helix axis
Sugar pucker C2'-endo

Start the tour with this view. Now look at this space filling view. reset; slab off; rotate z -140; rotate y -7; rotate x 71; zoom 144; select all; hbonds off; set bonds off; set bondmode and; select hetero; spacefill off; set hetero off; dots off; select dna; spacefill on; wireframe off; color magenta; select backbone; color yellow.

The backbone is yellow and the bases are magenta.

You can compare it with the other DNA forms by

You may include any references to papers as in: the use of JSmol in Proteopedia ^[1] or to the article describing Jmol ^[2] to the rescue.

Function

Disease

Relevance

Structural highlights

This is a sample scene created with SAT to , and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

ReferencesReferences

R. E. Dickerson, H. R. Drew, B. N. Conner, R. M. Wing, A. V. Fratini & M. L. Kopka (1982) The anatomy of A-, B-, and Z-DNA. Science 216: 475-485 ^[3]

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

James Nolan, Eric Martz

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