User:Cody Couperus/Sandbox 3
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RNA
Introduction
Products of Transcription
Post/Co-transcriptional modifications
Degradation pathways
Structure General
Primary Structure
Structure (building blocks)
RNARNA
IntroductionIntroduction
-single stranded polynucleic acid -Transcribed from DNA by family of RNA polymerases -Functional roles include functional transfer for protein synthesis, catalysis, cellular regulation -Degraded by....
Products of TranscriptionProducts of Transcription
Names/functional roles
Post/Co-transcriptional modificationsPost/Co-transcriptional modifications
Degradation pathwaysDegradation pathways
Structure GeneralStructure General
Summary of - how to build a 3D structure from a linear medium. Practical considerations. How to think about folded polymers. Backbone Ribose Bases + base pairing Forces: stacking (VDW), hydrogen bond, hydrophobic effect, electrostatic
Primary StructurePrimary Structure
Sequence Maybe some statistics?
Structure (building blocks)Structure (building blocks)
Coaxial helices Kink-turn Hook-turn Ribose zipper Kissing loops Hairpin loops Pseudoknots A-minor interactions A-major interactions Tetraloop-receptor motifs T-loop motif Triple stranded RNA RNA quadruplex structuers Metal chelation