Enzymes: enzyme-substrate complex

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Fructosa-bifosfato aldolasa (PDB 4ald)

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  • Enzyme: Fructose biphosphate aldolase
  • Substrate: fructose-1,6-biphosphate
  • Products: glyceraldehyde-3-phosphate and dihydroxiacetone-phosphate.
This shows secondary structures in Fructose biphosphate aldolase molecule.
This shows the polypeptide chain skeleton and amino acids R groups.
The polypeptide chain of this enzyme consist of .
Now, we are going to to highligth the enzyme
Active site is surrounded by
, i.e., fructose-1,6-biphosphate. fits into active site.
In this , fit between active site and substrate is best seen.
Zoom out to see a whole view.


All models we have analyzed show a of fructose biphosphate aldolase. Really, this enzyme is a oligomeric protein composed of four subunits that perform a .

ReferencesReferences

This page is based on the Proteopedia file 4ald.

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Alejandro Porto