4x1t

From Proteopedia
Revision as of 20:21, 10 February 2016 by OCA (talk | contribs)
Jump to navigation Jump to search

The crystal structure of Arabidopsis thaliana galactolipid synthase MGD1 in complex with UDPThe crystal structure of Arabidopsis thaliana galactolipid synthase MGD1 in complex with UDP

Structural highlights

4x1t is a 1 chain structure. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Activity:Monogalactosyldiacylglycerol synthase, with EC number 2.4.1.46
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[MGDG1_ARATH] Involved in the synthesis of the major structural component of photosynthetic membranes. Required for proper thylakoid membrane biogenesis. Does not discriminate between prokaryotic (18:1/16:0) or eukaryotic (18:2/18:2) 1,2-diacylglycerol species, but operates with some preference for the prokaryotic one.[1] [2] [3] [4]

References

  1. Jarvis P, Dormann P, Peto CA, Lutes J, Benning C, Chory J. Galactolipid deficiency and abnormal chloroplast development in the Arabidopsis MGD synthase 1 mutant. Proc Natl Acad Sci U S A. 2000 Jul 5;97(14):8175-9. PMID:10869420 doi:http://dx.doi.org/10.1073/pnas.100132197
  2. Marechal E, Awai K, Block MA, Brun D, Masuda T, Shimada H, Takamiya K, Ohta H, Joyard J. The multigenic family of monogalactosyl diacylglycerol synthases. Biochem Soc Trans. 2000 Dec;28(6):732-8. PMID:11171188
  3. Awai K, Marechal E, Block MA, Brun D, Masuda T, Shimada H, Takamiya K, Ohta H, Joyard J. Two types of MGDG synthase genes, found widely in both 16:3 and 18:3 plants, differentially mediate galactolipid syntheses in photosynthetic and nonphotosynthetic tissues in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10960-5. PMID:11553816 doi:http://dx.doi.org/10.1073/pnas.181331498
  4. Kobayashi K, Kondo M, Fukuda H, Nishimura M, Ohta H. Galactolipid synthesis in chloroplast inner envelope is essential for proper thylakoid biogenesis, photosynthesis, and embryogenesis. Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):17216-21. Epub 2007 Oct 16. PMID:17940034 doi:http://dx.doi.org/0704680104

4x1t, resolution 2.25Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA