Solution structure of the RhoGAP domain from human Rho GTPase activating protein 5 variantSolution structure of the RhoGAP domain from human Rho GTPase activating protein 5 variant

Structural highlights

2ee4 is a 1 chain structure with sequence from Human. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Activity:Small monomeric GTPase, with EC number 3.6.5.2
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, TOPSAN

Function

[RHG05_HUMAN] GTPase-activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of RASA1/p120GAP.

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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OCA