3ihj

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Human alanine aminotransferase 2 in complex with PLPHuman alanine aminotransferase 2 in complex with PLP

Structural highlights

3ihj is a 1 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:GPT2, AAT2, ALT2 (HUMAN)
Activity:Alanine transaminase, with EC number 2.6.1.2
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[ALAT2_HUMAN] Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Yang RZ, Blaileanu G, Hansen BC, Shuldiner AR, Gong DW. cDNA cloning, genomic structure, chromosomal mapping, and functional expression of a novel human alanine aminotransferase. Genomics. 2002 Mar;79(3):445-50. PMID:11863375 doi:http://dx.doi.org/10.1006/geno.2002.6722

3ihj, resolution 2.30Å

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