Crystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoACrystal Structure of human type-I N-myristoyltransferase with bound myristoyl-CoA

Structural highlights

3iu1 is a 2 chain structure with sequence from Human. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:NMT, NMT1 (HUMAN)
Activity:Glycylpeptide N-tetradecanoyltransferase, with EC number 2.3.1.97
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[NMT1_HUMAN] Adds a myristoyl group to the N-terminal glycine residue of certain cellular and viral proteins.

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

3iu1, resolution 1.42Å

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OCA