Proteopedia

2doo

Revision as of 23:24, 8 February 2016 by OCA (talk | contribs)

The structure of IMP-1 complexed with the detecting reagent (DansylC4SH) by a fluorescent probeThe structure of IMP-1 complexed with the detecting reagent (DansylC4SH) by a fluorescent probe

Structural highlights

2doo is a 2 chain structure with sequence from "bacillus_marcescens"_(bizio_1823)_trevisan_in_de_toni_and_trevisan_1889 "bacillus marcescens" (bizio 1823) trevisan in de toni and trevisan 1889. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:BLAIMP-1 ("Bacillus marcescens" (Bizio 1823) Trevisan in de Toni and Trevisan 1889)
Activity:Beta-lactamase, with EC number 3.5.2.6
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[BLAB_SERMA] Confers resistance to imipenem and broad-spectrum beta-lactams. Also hydrolyzes carbapenems.

Evolutionary Conservation

 

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

2doo, resolution 2.43Å

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