3dgi

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Crystal structure of F87A/T268A mutant of CYP BM3Crystal structure of F87A/T268A mutant of CYP BM3

Structural highlights

3dgi is a 2 chain structure with sequence from Atcc 14581. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:CYP102A1, cyp102 (ATCC 14581)
Activity:Unspecific monooxygenase, with EC number 1.14.14.1
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum

Function

[CPXB_BACME] Functions as a fatty acid monooxygenase. Catalyzes hydroxylation of medium and long-chain fatty acids at omega-1, omega-2 and omega-3 positions, with optimum chain lengths of 12-16 carbons (lauric, myristic, and palmitic acids). The reductase domain is required for electron transfer from NADP to cytochrome P450.

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3dgi, resolution 1.95Å

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