Circadian clock protein

File:2gbl.png

Circadian clock protein KaiC 2gbl

Circadian clock proteins measure out the 24 hour circadian rhythm. In cyanobacteria protein KaiA stimulates KaiC which adds phosphate groups to itself. Then KaiC binds to KaiB which inactivates KaiA and causes the number of phosphate groups on KaiC to drop slowly. KaiB disconnects allowing KaiA to start the cycle again. For details of KaiC see Circadian Clock Protein KaiC.

3D Structures of circadian clock protein3D Structures of circadian clock protein

Updated on 08-December-2015

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• KaiA
  • 1r5q – NoKaiA - Nostoc
    
  • 1m2e, 1m2f – SeKaiA N terminal – Synechococcus elongatus - NMR
    
  • 1q6a, 1q6b – SeKaiA C terminal - NMR
    
  • 1v2z – SeKaiA C terminal
    
  • 1r8j – SeKaiA
    
  • 1suy, 1sv1 – SeKaiA C terminal + KaiC peptide - NMR
    
  • 4g86 – SeKaiA + DBMIB
    
• KaiB
  • 1r5p – NoKaiB
    
  • 1wwj – SyKaiB - Synechocystis
    
  • 1vgl, 2qke, 4kso – SeKaiB
    
• KaiC
  • 1tf7, 2gbl – SyKaiC
    
  • 1u9i, 3dvl, 3jzm, 3k09, 3k0a, 3k0c, 3k0e, 3k0f, 3s1a, 4dug, 4ijm – SeKaiC (mutant)