Adhesin

Function Adhesins (Adh) are surface components of bacteria which facillitate adhesion to surfaces or other cells. Adh are specific surface recognition protein and are regarded as virulence factors. Disease Bacterial pathogens use adhesins as a major factor in adhesion-based virulence. Adhesins serve as vaccine targets since they are essential to infection.

spinqualitylabelsall models Adhesin PsaA complex with galactose (PDB ID 4f8p) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

3D Structures of adhesin3D Structures of adhesin

Updated on 06-December-2015

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• Fimbrial adhesin
  • 4k0o, 2bs8 – EcF17b-G lectin domain – Escherichia coli
    
  • 4b4p, 4bwo – EcFedF lectin domain
    
  • 4b4q, 4b4r – EcFedF lectin domain + hexasaccharide
    
  • 4w6w, 4w6x, 4w6y – EcFedF lectin domain + nanobody
    
  • 1psz – SpPsaA + Zn – Streptococcus pneumonia
    
  • 3ztt – SpPsaA + Mn
    
  • 4utp, 4uto – SpPsaA + Cd
    
  • 3zk7 – SpPsaA
    
  • 3zk8, 3zk9, 3zka – SpPsaA (mutant)
    
  • 2bs7 – EcF17b-G lectin domain + chitobiose
    
  • 3ffo – EcF17b-G lectin domain + GlcNac-Man
    
  • 4f8l – YpPsaA + galactose + inhibitor – Yersinia pestis
    
  • 4f8n – YpPsaA + galactose + phosphate choline
    
  • 4f8o – YpPsaA + lactose + inhibitor
    
  • 4f8p – YpPsaA + galactose
    
• Collagen adhesin (CAdh)
  • 1amx – SaCAdh CBD – Staphylococcus aureus
    
  • 1d2o – SaCAdh B1 repeat unit
    
  • 1d2p – SaCAdh B1-B2 repeat units
    
  • 2f68 – SaCAdh extracellular domain
    
  • 2f6a – SaCAdh extracellular domain + collagen
    
  • 2okm – CAdh CBD – Enterococcus faecalis
    
  • 1p9h – YeYadA CBD – Yersinia enterocolitica
    
  • 3h7x – YeYadA stalk domain
    
  • 3h7z – YeYadA stalk domain (mutant)
    
  • 3lt6, 3lt7 – YeYadA coiled coil
    
  • 2lme – YeYadA coiled coil - NMR
    
• Adhesin
  • 2odl – Adh secretion domain – Haemophilus influenzae